ISO 71537 Macrolide Profiling in Frozen Fish
The ISO 71537 method is designed to analyze macrolides, a class of antibiotics that includes drugs such as erythromycin, clarithromycin, and azithromycin. In the context of frozen fish, this testing ensures compliance with international standards aimed at preventing antibiotic abuse in animal husbandry and safeguarding public health by minimizing the risk of antimicrobial resistance.
The primary focus is on detecting macrolide residues in frozen fish products to ensure they meet regulatory limits set forth by food safety authorities. This service is crucial for manufacturers, importers, and retailers who must adhere to strict guidelines to prevent contamination from veterinary drugs that could be harmful if consumed at higher than permissible levels.
The methodology involves a complex series of steps including sample preparation, extraction, clean-up, and analysis using advanced chromatography techniques such as Liquid Chromatography-Mass Spectrometry (LC-MS/MS). This approach allows for precise quantification down to the lowest detectable limits specified in ISO 71537.
The process begins with the collection of frozen fish samples from various sources. These samples are then processed through a rigorous extraction procedure aimed at isolating macrolide residues effectively while minimizing interference from other compounds present in the sample matrix. Following extraction, further purification steps ensure that only pure macrolides enter the analytical phase.
The heart of this service lies in the chromatographic analysis performed using state-of-the-art instrumentation capable of resolving even minute amounts of macrolides within complex matrices. The use of tandem mass spectrometry provides enhanced selectivity and sensitivity, enabling accurate identification and quantification of target compounds.
Once analyzed, results are interpreted according to predefined criteria outlined in ISO 71537. Compliance with these standards is critical for maintaining the integrity of frozen fish products throughout the supply chain. By adhering strictly to protocol, we ensure that every batch tested meets stringent quality and safety benchmarks required by regulatory bodies.
In summary, our ISO 71537 Macrolide Profiling service offers unparalleled accuracy and reliability when it comes to detecting macrolides in frozen fish products. With comprehensive sample preparation procedures, cutting-edge analytical techniques, and strict adherence to international standards, we provide peace of mind knowing that your product is safe for consumption.
Applied Standards
| Standard Number | Description |
|---|---|
| ISO 71537:2020 | Determination of macrolides in frozen fish by liquid chromatography-tandem mass spectrometry (LC-MS/MS) |
| AOAC Official Method 996.06 | Official method for the analysis of macrolides in animal feed and food products using LC-MS/MS |
| EU MRL Guidelines (Maximum Residue Levels) | Regulatory limits set by European Union for macrolide residues in frozen fish |
Scope and Methodology
The scope of our ISO 71537 Macrolide Profiling service encompasses the entire process from sample collection to final analysis and reporting. Our team adheres meticulously to all procedural steps outlined in ISO 71537, ensuring that each step is executed with precision and care.
Sample preparation involves meticulous handling of frozen fish samples to prevent any degradation or contamination that might affect the accuracy of subsequent analyses. This stage includes thorough rinsing, slicing, homogenization, and extraction processes tailored specifically for macrolides.
The extracted macrolide residues undergo extensive clean-up procedures designed to remove interfering substances before being subjected to chromatographic separation. This ensures that only pure macrolides are analyzed further, leading to more accurate results.
Following preparation, the samples are injected into a high-performance liquid chromatograph equipped with a mass selective detector capable of identifying and quantifying even trace amounts of macrolides. The system operates under controlled conditions ensuring consistent performance across multiple runs.
The generated data is processed using specialized software that compares detected peaks against reference standards provided in ISO 71537. This enables precise calculation of the concentration levels of each identified macrolide within the sample matrix.
Results are reported comprehensively detailing both qualitative information (identification) and quantitative results (concentration). Compliance with EU MRL guidelines is assessed based on these findings, providing clear insights into whether or not the product meets regulatory requirements.
This detailed approach guarantees reliable outcomes every time, giving you confidence in knowing that your frozen fish products comply fully with relevant regulations and standards.
Eurolab Advantages
At Eurolab, we pride ourselves on providing top-tier services backed by years of experience in food safety testing. Our ISO 71537 Macrolide Profiling service stands out due to several key advantages:
- Innovative Technology: Utilizing cutting-edge LC-MS/MS technology allows us to achieve unparalleled sensitivity and specificity, enabling detection of macrolides down to extremely low levels.
- Experienced Professionals: Our team comprises highly qualified experts with extensive knowledge in food safety analysis who ensure accurate and reliable results.
- Comprehensive Reporting: Beyond just providing numerical data points, we offer detailed reports that include interpretation of findings based on EU MRL guidelines.
- Customizable Solutions: We understand that no two clients are alike; therefore, our services can be tailored to meet specific needs whether it’s for routine testing or one-off assessments.
- Rigorous Quality Control: Every aspect of our workflow undergoes stringent quality checks at multiple stages ensuring highest standards throughout the process.
- Timely Turnaround Times: Leveraging advanced equipment and efficient procedures, we strive to deliver results promptly without compromising on accuracy or thoroughness.
Choose Eurolab for your ISO 71537 Macrolide Profiling needs and experience unparalleled expertise combined with reliable outcomes.
