ISO 46325 Tetracycline Residue Profiling in Honey Drinks
The ISO/IEC 17025 accredited laboratory provides comprehensive testing services for detecting tetracycline residues in honey drinks. This service ensures that food products comply with international standards and meet consumer expectations regarding safety and quality.
ISO 46325 is a method specifically designed to profile tetracycline residues in honey and its derived products, including honey drinks. The procedure involves several steps that ensure accurate detection of tetracycline residues down to the limit specified by this standard. Our laboratory employs advanced analytical techniques to achieve precise results, which are crucial for maintaining product integrity.
The testing process begins with sample preparation, where we carefully select and prepare representative samples from various batches or lots of honey drinks. This step ensures that the analysis reflects the overall quality of the product. Following this, our lab utilizes high-performance liquid chromatography (HPLC) coupled with mass spectrometry (MS/MS) to detect tetracycline residues. HPLC is preferred for its ability to separate complex mixtures into individual components, while MS/MS enhances sensitivity and specificity, enabling accurate quantification of the target compounds.
Once the samples are analyzed, our laboratory generates detailed reports that include both qualitative and quantitative data. These reports serve as valuable tools for quality control departments, helping them ensure compliance with regulatory requirements. Compliance officers can use these findings to make informed decisions about product formulations and sourcing, thereby protecting their brand’s reputation.
R&D engineers benefit from our services by gaining insights into the presence and levels of tetracycline residues in various honey drink formulations. This information is essential for optimizing production processes and developing new products that meet stringent safety standards. Additionally, procurement teams can leverage these results to select suppliers who adhere strictly to best practices regarding veterinary drug use.
Our commitment to accuracy and reliability extends beyond mere detection; it encompasses thorough validation of our methods against recognized international standards such as ISO 46325. By adhering to these rigorous protocols, we guarantee that every test conducted at our facility meets the highest scientific and regulatory expectations.
- Customer Impact: Ensures compliance with international regulations.
- Enhances brand reputation through consistent product quality.
- Aids in maintaining public trust by providing transparent reporting on safety metrics.
- Supports continuous improvement initiatives within supply chain management systems.
Scope and Methodology
The scope of ISO 46325 Tetracycline Residue Profiling in Honey Drinks encompasses the analysis of tetracycline residues present in honey drinks. This includes identifying the presence, concentration, and type of tetracycline derivatives that may have been introduced unintentionally during production or handling.
Our methodology adheres strictly to ISO 46325 guidelines, which outline specific procedures for sample preparation, extraction, cleanup, and analysis using HPLC-MS/MS technology. The workflow starts with receiving the honey drink samples followed by thorough documentation of each step taken throughout the analytical process.
Sample preparation involves dilution if necessary to achieve optimal concentrations suitable for detection without compromising precision or accuracy. Extraction follows next, typically achieved via solid phase extraction (SPE) cartridges designed specifically for matrix removal prior to injection into HPLC-MS/MS instrumentation.
The cleaned extracts are then injected onto the reversed-phase column within an HPLC system configured with UV detection and electrospray ionization MS interfacing. Data acquisition occurs in positive ion mode, focusing on characteristic ions corresponding to tetracycline derivatives of interest as per ISO 46325 requirements.
Finally, post-run processing involves alignment of chromatograms based upon retention times calculated according to established reference standards. Quantification takes place using calibration curves prepared beforehand covering the full range expected for each analyte under investigation.
Quality and Reliability Assurance
At our ISO/IEC 17025 accredited facility, quality and reliability are paramount in delivering accurate test results. We have implemented robust quality management systems (QMS) to ensure consistent performance across all aspects of the testing process.
A key component of our QMS is method validation, which involves demonstrating that analytical methods meet predefined specifications for accuracy, precision, linearity, range, specificity, detection limit, and quantitation limit. For ISO 46325 Tetracycline Residue Profiling in Honey Drinks specifically, we have validated our approach following the procedures outlined in this international standard.
We also participate in proficiency testing programs organized by recognized organizations such as A2LA (American Association for Laboratory Accreditation). These programs provide external assessments of our analytical capabilities and help identify areas for improvement. Participation ensures continuous enhancement of our laboratory’s technical competence.
In addition to method validation and proficiency testing, we maintain strict quality control measures at every stage of sample handling, preparation, analysis, and reporting. Our dedicated staff undergo regular training sessions led by experienced professionals who stay updated on the latest developments in analytical chemistry and regulatory requirements.
