ISO 19619 Detection of Milk Allergens in Food by LC-MS
The detection and quantification of milk allergens in food products are critical to ensuring consumer safety, especially for individuals with lactose intolerance or milk allergies. ISO 19619 provides a standardized approach using Liquid Chromatography-Mass Spectrometry (LC-MS) for the identification of milk allergens such as casein and whey proteins.
Our laboratory adheres strictly to this international standard, ensuring accurate detection and quantification of these components. The process involves multiple steps: sample preparation, extraction, purification using LC-MS/MS, data analysis, and reporting results in accordance with ISO 19619 guidelines.
The significance of milk allergen testing cannot be overstated, particularly for food manufacturers who must comply with stringent regulations to protect public health. This service is vital not only for compliance but also to maintain a positive brand image and trust among consumers.
LC-MS technology offers high sensitivity and specificity, making it an ideal method for detecting trace levels of milk allergens in complex matrices like processed foods. Our laboratory uses state-of-the-art instruments from reputable manufacturers such as Thermo Fisher Scientific and Waters Corporation to ensure reliable results.
The procedure typically begins with the collection of raw samples followed by homogenization and filtration to remove particulates, which may interfere with analytical processes. After extraction using appropriate solvents like methanol or acetone, proteins are concentrated through centrifugation before further purification steps if necessary.
LC-MS analysis involves injecting prepared extracts onto a reversed-phase HPLC column where they separate based on their properties such as polarity and molecular weight. Once separated, the eluted compounds pass into the mass spectrometer where fragmentation patterns characteristic of specific peptides allow identification and quantification.
Our laboratory follows stringent quality control measures throughout this process to ensure accuracy and reliability. This includes internal validation studies comparing our results against certified reference materials whenever available; inter-laboratory comparisons with other accredited labs; regular calibration checks on analytical equipment; proficiency testing exercises organized by external bodies like A2LA or NIST.
Results are reported in accordance with ISO 19619, providing clients with clear, actionable insights regarding the presence and concentration levels of milk allergens within their products. These data can inform product reformulations aimed at reducing allergen content where necessary while ensuring adequate labeling according to relevant regulations such as FDA CFR Title 21 Part 1301 et seq or EU Regulation (EU) No 1169/2011.
By leveraging our expertise in this area, organizations can safeguard their reputation and meet regulatory requirements confidently. Our team of experienced scientists combines deep knowledge of food chemistry with cutting-edge analytical techniques to deliver robust evidence supporting claims about allergen-free status or partial reduction strategies implemented during product development phases.
In summary, adherence to ISO 19619 through LC-MS technology represents a cornerstone in modern allergen management practices. It enables precise quantification tailored specifically for regulatory compliance purposes and consumer protection goals across various sectors including pharmaceuticals, nutraceuticals, cosmetics, pet food, and more.
Eurolab Advantages
At Eurolab, we pride ourselves on offering unparalleled expertise in allergen testing services. Our team comprises highly trained professionals who stay abreast of the latest developments within this rapidly evolving field. By choosing us as your partner for ISO 19619 compliance, you benefit from:
- State-of-the-art instrumentation supplied by leading manufacturers.
- Pioneering methodologies that ensure precision and accuracy in all analyses.
- A commitment to continuous improvement through ongoing training programs for staff.
- Dedicated support services available round the clock via our toll-free helpline.
We also offer comprehensive consulting services designed specifically around your unique needs, helping you navigate complex regulatory landscapes effectively. Whether it's implementing new procedures or optimizing existing ones, Eurolab has the resources and experience required to assist seamlessly throughout every stage of project execution.
Customer Impact and Satisfaction
Our clients value our commitment to excellence when it comes to allergen testing. By leveraging ISO 19619-compliant LC-MS technology, we provide them with peace of mind knowing that their products are rigorously analyzed for safety compliance. Here’s how our services positively impact customers:
- Reduces the risk of recalls due to undeclared allergens.
- Safeguards brand reputation by demonstrating adherence to strict regulatory standards.
- Enhances consumer trust through transparent communication about product composition.
- Aids in meeting voluntary commitments beyond mandatory requirements set forth by governing bodies worldwide.
Moreover, our flexible approach allows customers to tailor testing packages according to their specific business objectives. From routine monitoring to one-off assessments conducted upon request, Eurolab ensures that each client receives personalized attention and support throughout the entire process.
International Acceptance and Recognition
The ISO 19619 standard is widely recognized internationally for its robustness in detecting milk allergens via LC-MS technology. Its acceptance extends across multiple countries including but not limited to:
- Australia – where food safety legislation emphasizes the importance of proper labeling practices.
- Canada – which mandates strict controls on imported goods containing potential allergens.
- The European Union – where member states implement harmonized policies regarding traceability and transparency in ingredient declarations.
- Japan – known for its stringent requirements concerning food additives and contaminants.
- The United States – under the FDA's Food Safety Modernization Act (FSMA), which emphasizes prevention-based strategies including allergen control plans.
Beyond governmental regulations, many private companies also adopt these standards out of ethical considerations towards consumers with sensitivities or intolerances. Thus, using ISO 19619 ensures compatibility not just domestically but globally as well.
