ISO 40367 3-MCPD Residue Analysis in Infant Formula
The analysis of 3-monochloropropane-1,2-diol (3-MCPD) residues in infant formula is a critical aspect of ensuring food safety and quality. This stringent test aligns with the international standard ISO 40367, which specifies the methodology for determining 3-MCPD levels in infant foods. The significance of this analysis cannot be overstated, as even trace amounts of 3-MCPD can have adverse health effects on infants due to their more sensitive physiology.
The process involves several steps: first, the sample is prepared by thoroughly homogenizing it to ensure an accurate and representative test result. Next, a precise amount is weighed out according to predefined protocols for the analysis. This preparation ensures that any subsequent steps are conducted with consistent and reliable starting materials.
Once the sample is ready, it undergoes extraction using either solvent-based or solid-phase extraction methods, followed by derivatization if necessary, depending on the analytical technique chosen—typically gas chromatography coupled with mass spectrometry (GC-MS). The extracted compounds are then injected into the GC-MS for quantification. This advanced instrumentation allows for highly sensitive detection and accurate measurement of 3-MCPD residues.
The results from this analysis provide critical insights into the quality control measures needed to maintain compliance with regulatory standards such as ISO 40367. Compliance is paramount in the infant formula sector, where even small deviations can have significant implications for public health. This service ensures that manufacturers adhere to these stringent requirements, thereby safeguarding consumer confidence and safety.
Our laboratory adheres strictly to international norms and uses state-of-the-art equipment to deliver accurate and reliable test results consistently. By leveraging this expertise, we contribute significantly to the overall quality assurance of infant formula products, ensuring they meet rigorous safety standards.
Scope and Methodology
The scope of 3-MCPD residue analysis in infant formula encompasses a wide range of analytical techniques tailored specifically for this critical test. The methodology outlined by ISO 40367 provides detailed guidelines on sample preparation, extraction procedures, derivatization steps (if required), instrumental analysis using GC-MS, and the subsequent interpretation of results.
| Step | Action |
|---|---|
| Sample Preparation | Homogenize sample thoroughly to ensure uniformity. |
| Weighing | Accurately weigh out the specified amount of prepared sample. |
| Extraction | Use solvent-based or solid-phase extraction methods as appropriate. |
| Derivatization | Perform if required for optimal GC-MS performance. |
| Instrumental Analysis | Analyze using gas chromatography coupled with mass spectrometry (GC-MS). |
| Data Interpretation | Interpret results against ISO 40367 specified limits. |
| Instrumental Parameters | Values |
|---|---|
| GC Column | DB-5 or equivalent, 30 m x 0.25 mm ID |
| Carrier Gas Flow | 1 ml/min helium |
| Injection Method | Splitless injection at 250°C |
| Detector Temperature | 300°C |
| Mass Spectrometer Conditions | Electron Ionization (EI) mode; scan range: m/z 40-650 |
Benefits
- Ensures compliance with ISO 40367 standards.
- Promotes infant health and safety by minimizing exposure to harmful substances.
- Provides reliable data for quality assurance programs.
- Enhances reputation among consumers, regulators, and competitors.
- Aids in the continuous improvement of manufacturing processes.
- Supports regulatory compliance and market entry requirements.
- Facilitates better-informed decision-making regarding product formulations.
