ISO 40367 3 MCPD Detection in Seafood Products Validation Method Development Test
The ISO 40367:2019 standard provides a method for the determination of monochloroacetic acid (MCPD) esters in foodstuffs, including seafood products. This specific service focuses on validating methods used to detect MCPD esters according to this international standard. Our laboratory specializes in ensuring that the analytical processes employed are robust and accurate, delivering reliable data for quality assurance and compliance purposes.
The importance of this test cannot be overstated. MCPDs are a group of compounds that can form during food processing or storage and may pose health risks if present at high levels. Seafood products, in particular, require stringent testing to ensure they meet the safety standards set forth by various regulatory bodies like the European Union’s Scientific Committee on Food.
Our laboratory uses state-of-the-art equipment and techniques to perform this validation test. Our team of experts ensures that all samples are handled with care, from initial sampling through final analysis. This process includes careful extraction of MCPD esters using appropriate solvents followed by quantification via high-performance liquid chromatography (HPLC) coupled with tandem mass spectrometry (MS/MS).
One of the key aspects of our service is ensuring that the methods we validate are not only compliant with ISO 40367 but also optimized for use in your specific laboratory environment. This may involve adapting the extraction procedure or adjusting the mobile phase composition to better suit the nature of the seafood samples being tested.
The results from this validation process can be used to improve internal quality control procedures and ensure consistency across batches of products. Additionally, having validated methods allows companies to meet regulatory requirements more easily while maintaining a high standard of product safety.
Our team works closely with clients throughout the entire validation process, providing technical support as needed. Whether you're looking to validate an existing method or develop a new one tailored specifically for your business needs, we have the expertise and resources to help you achieve your goals.
Applied Standards
The ISO 40367:2019 standard provides clear guidelines on how to carry out the extraction and quantification of MCPD esters in foodstuffs. This includes detailed information on sample preparation, solvent selection, analytical techniques, and data interpretation.
- Extraction solvents recommended for use include acetonitrile or methanol.
- Sample preparation should account for potential interference from other compounds present in the seafood samples.
The standard specifies that HPLC-MS/MS is the preferred analytical technique due to its high sensitivity and specificity. It also recommends the use of certified reference materials (CRMs) when calibrating the instrument and validating the method.
Our laboratory adheres strictly to these standards during every step of the validation process, ensuring that all results are accurate and reliable.
Scope and Methodology
The scope of this service is limited to the validation of methods used for detecting MCPD esters in seafood products. This includes both single-component and multi-component analyses as specified in ISO 40367:2019.
- Samples must be representative of the product being tested.
- The method should produce consistent results over time.
The methodology involves several key steps:
- Sample collection and preservation.
- Extraction of MCPD esters using appropriate solvents.
- Cleanup of extracts if necessary to remove interfering components.
- Detection and quantification via HPLC-MS/MS analysis.
At each stage, our team ensures that all procedures are followed precisely as outlined in the standard. This includes using certified reference materials (CRMs) for calibration purposes and conducting blank experiments to verify sample integrity.
