Hepatic Enzyme Panel Testing in Companion Animal Diagnostics
The hepatic enzyme panel is a critical diagnostic tool used to assess liver function and identify potential issues in companion animals, such as dogs and cats. This comprehensive test measures several key enzymes and proteins that provide insights into the health of an animal's liver. Proper diagnosis can lead to early intervention and improved outcomes for affected pets.
肝功能酶联测定（Hepatic Enzyme Panel Testing）在伴侣动物诊断中扮演着至关重要的角色。这项全面的测试测量多个关键酶和蛋白质，为评估宠物肝脏健康状况提供了宝贵的见解。适当的诊断可以实现早期干预，并改善受感染动物的生活质量。
The hepatic enzyme panel includes tests for alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), and others. These enzymes are indicators of liver cell damage, inflammation, or disease. Elevated levels can suggest various conditions such as hepatitis, cholangitis, or hepatic necrosis.
肝功能酶联测定包括对丙氨酸氨基转移酶（ALT）、天冬氨酸氨基转移酶（AST）、碱性磷酸酶（ALP）、γ-谷氨酰转肽酶（GGT）等关键酶和蛋白质的检测。这些酶是肝脏细胞损伤、炎症或疾病的重要指标。升高水平可以暗示多种情况，如肝炎、胆管炎或肝坏死。
The test is performed on blood samples, which are typically collected from the animal's jugular vein or saphenous vein. The sample must be handled carefully to minimize hemolysis and ensure accurate results. Proper specimen preparation includes centrifugation of the collected blood into serum for analysis.
肝功能酶联测定通常通过从动物的颈静脉或大隐静脉采集血液样本进行。为了确保结果准确，处理样本时必须小心，尽量避免溶血现象的发生。正确的标本准备包括将收集的血液离心分离出血清用于分析。
The testing process involves several steps, including sample collection, transport to the laboratory, preparation of the specimen for analysis, and finally, running the test on specialized instruments. The results are typically available within 24-72 hours after the sample is received in the lab.
测试过程包括样本采集、运送到实验室、准备标本进行分析，最后在专用仪器上运行测试。结果通常在样品送至实验室后的24到72小时内可以获得。
The hepatic enzyme panel is essential for diagnosing and monitoring liver diseases in companion animals. It helps veterinarians make informed decisions about treatment plans, monitor the effectiveness of ongoing therapies, and identify any potential complications.
肝功能酶联测定对于诊断和监测伴侣动物的肝脏疾病至关重要。它帮助兽医做出关于治疗方案的信息决策，监控正在进行疗法的效果，并识别任何潜在并发症。
Applied Standards
The hepatic enzyme panel testing in companion animal diagnostics follows internationally recognized standards to ensure accuracy and consistency across laboratories. The most commonly used standards include ISO 15189, which sets quality management requirements for medical laboratories; EN ISO/IEC 17025, which specifies general requirements for the competence of testing and calibration laboratories; and CLSI (Clinical and Laboratory Standards Institute) guidelines.
肝功能酶联测定在伴侣动物诊断中的应用遵循国际上公认的准则，以确保实验室间结果的准确性和一致性。最常使用的标准包括ISO 15189，它为医学实验室设定质量管理要求；EN ISO/IEC 17025，则规定了测试和校准实验室的能力通用要求；还有CLSI（临床与实验室标准研究所）指南。
Scope and Methodology
The scope of hepatic enzyme panel testing in companion animal diagnostics includes the analysis of several key enzymes and proteins that are indicative of liver health. The methodology involves collecting blood samples from the animal, processing them into serum, and then performing a series of tests using specialized instruments.
肝功能酶联测定在伴侣动物诊断中的范围包括对多个关键酶和蛋白质的分析，这些指标可指示肝脏健康状况。方法学涉及从动物采集血液样本、将它们处理成血清，然后使用专用仪器进行一系列测试。
The specific enzymes and proteins measured include alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), lactate dehydrogenase (LDH), bilirubin, and others. These parameters are chosen based on their sensitivity to changes in liver function.
所测量的具体酶和蛋白质包括丙氨酸氨基转移酶（ALT）、天冬氨酸氨基转移酶（AST）、碱性磷酸酶（ALP）、γ-谷氨酰转肽酶（GGT）、乳酸脱氢酶（LDH）、胆红素等。这些参数是根据它们对肝脏功能变化的敏感性选择的。
The testing process is highly standardized and involves several key steps. First, the blood sample is collected from the animal and transported to the laboratory for analysis. Next, the sample is prepared by centrifugation into serum. Finally, the serum is tested using specialized instruments that can measure multiple parameters simultaneously.
测试过程高度标准化，包括几个关键步骤。首先，从动物采集血液样本并运送到实验室进行分析。然后，通过离心将样品处理成血清。最后，使用可以同时测量多个参数的专用仪器对血清进行测试。
Benefits
The hepatic enzyme panel testing in companion animal diagnostics offers numerous benefits, including early detection of liver disease, accurate diagnosis, and timely intervention. Early identification allows for the initiation of appropriate treatment, which can significantly improve the prognosis of the affected animals.
肝功能酶联测定在伴侣动物诊断中的应用提供了诸多益处，包括早期检测肝脏疾病、准确诊断和及时干预。早期识别可以启动适当的治疗，这将显著改善受影响动物的预后。
The test also helps in monitoring the progression of liver disease and assessing the effectiveness of treatment. This is particularly important for chronic conditions where regular follow-up is necessary to ensure ongoing health.
该测试还有助于监测肝病的发展进程，并评估治疗的有效性。这对于需要定期随访以确保持续健康的慢性疾病尤为重要。
In addition, hepatic enzyme panel testing can help differentiate between various forms of liver disease and provide a more comprehensive understanding of the underlying pathology. This information is invaluable for developing tailored treatment plans.
此外，肝功能酶联测定还可以帮助区分各种形式的肝病，并提供对潜在病理学更全面的理解。这些信息对于制定个性化的治疗计划至关重要。
