USP Tablet Dissolution in Biorelevant Media Testing
The USP Tablet Dissolution Test is a critical analytical procedure used to evaluate the dissolution characteristics of tablets, particularly those intended for oral solid dosage forms. Dissolution testing ensures that active pharmaceutical ingredients (APIs) are released from the dosage form at rates consistent with the therapeutic effect. This test focuses on biorelevant media, which more closely mimic in vivo conditions compared to conventional artificial buffers.
The USP Test is governed by specific USP chapters and monographs. These guidelines specify the dissolution apparatus (e.g.,桨桨