ISO 21362 Nanoparticle Size Distribution for Inhalation Studies
The ISO 21362 standard provides a comprehensive method for determining the size distribution of nanoparticles intended for inhalation exposure studies. This is critical in ensuring that the test conditions accurately reflect real-world scenarios, which is essential for developing safe and effective products.
Inhalation studies are pivotal in evaluating the respiratory toxicity and other health effects of nanomaterials. The ISO 21362 protocol ensures that the particle size distribution data obtained can be reliably used to assess potential risks associated with inhalation exposure. This standard is particularly important for industries such as pharmaceuticals, cosmetics, and environmental science.
The test involves several key steps: sample preparation, sampling, analysis using laser diffraction or other suitable methods, and the interpretation of results. Sample preparation should be conducted in a controlled environment to minimize contamination and ensure accurate size distribution measurements. Sampling is typically performed under conditions that replicate real-world inhalation exposure.
The accepted particle size range for this test generally falls between 10 nm and 10 µm, although the exact limits may vary depending on specific application requirements. The primary focus of ISO 21362 is to provide a robust framework for determining the mass median diameter (MMD) and geometric standard deviation (GSD).
| Application | Description |
|---|---|
| Inhalation Toxicology Studies | Determining the potential respiratory effects of nanoparticles. |
| Regulatory Compliance | Meeting regulatory requirements for nanoparticle testing. |
| R&D in Nanoparticle Formulations | Evaluating the effectiveness of different particle size distributions. |
| Safety Assessment | Assessing the safety profile of nanomaterials for inhalation exposure. |
Eurolab Advantages
At Eurolab, we bring over two decades of experience in nanomaterials testing to ensure that our services meet the highest standards. Our team of experts has extensive knowledge and expertise in various aspects of nanoparticle size distribution analysis.
- Comprehensive Understanding: We have a deep understanding of the ISO 21362 protocol, enabling us to provide accurate and reliable testing results.
- State-of-the-Art Facilities: Our laboratories are equipped with advanced analytical instruments, ensuring precise measurements and accurate data.
- Patient Service Delivery: We offer flexible scheduling and personalized service to meet your specific needs.
Why Choose This Test
Selecting the ISO 21362 nanoparticle size distribution test is advantageous due to its robustness and reliability. Here are some reasons why:
- Compliance with Regulatory Standards: Adherence to ISO standards ensures compliance with international regulations.
- Accurate Data: Precise size distribution measurements provide reliable data for risk assessment and product development.
- Rapid Turnaround Times: Our efficient processes ensure quick delivery of results, facilitating timely decision-making.
Use Cases and Application Examples
| Application | Description |
|---|---|
| Pharmaceutical Nanoparticles | Evaluating the efficacy of nanoformulated drugs. |
| Cosmetics and Personal Care Products | Assessing the safety profile of nanoparticulate ingredients. |
| Aerosolized Nanomaterials | Determining the effects of aerosolized nanoparticles on respiratory health. |
